Although predicating on the FUE method, DHI hair transplantation is applied in a slightly different manner. The most important feature that makes this method different is that the treatment is done without shaving hair. While typical FUE methods involve 3 steps comprised of Graft Collection, Channel Creation and Follicle Transplant, DHI hair transplant method differs in the Channel Creation step, which is not performed as a separate action. In DHI method grafts are collected by a medical pen under local anaesthesia and then channel creation and follicle transplantation actions are performed at once in a process of seconds. Hair transplantation process performed in 3 steps in typical FUE technique is reduced to 2 steps in DHI technique thanks to use of a medical pen.

Sapphire percutaneous hair transplantation is a new hair transplantation technique that is based on the use of a natural sapphire stone (crystal) to create the channels for hair graft transplantation without damaging the skin. In the Sapphire Percutaneous method, a singular cavity is created for each individual follicle, which results in a natural look. Transplanted hair follicles do not move. Thanks to the creation of an individual cavity for each individual follicle the result is a thicker and more natural appearance. In typical hair transplantation the number of follicles that can be grafted on an area of 1 square centimetre is around 35-40, while the number follicles that can be grafted on the same area can reach up to 70-80. This technique differs according to the skin structure of the person who needs hair transplantation and it is done by a titanium handled and sapphire grooving pen.